Frozen stomach and rumen contents should be analyzed for the pesticide. It is common in developing countries. 2-PAM (1 to 2 g in adults; 20 to 40 mg/kg in children) is given over 15 to 30 minutes IV after exposure to an organophosphate or carbamate because, frequently, whether the poison is an organophosphate or carbamate is unknown at the time of treatment. Sick dogs have a depressed immunity system and exposure to any insecticide can affect them greatly. Signs and symptoms of organophosphate poisoning can be divided into three broad categories: (1) muscarinic effects, (2) nicotinic effects, and (3) central nervous system (CNS) effects. The following is a more comprehensive list of signs and symptoms that may be encountered in a person exposed to a nerve agent or OP pesticide. Pralidoxime (2-PAM) is given after atropine to relieve neuromuscular symptoms. Organophosphate poisoning is a neurological syndrome caused by exposure to organophosphate chemicals like those found in insecticides, herbicides, and some nerve agents. The present review discusses the structure of the anticholinesterase organophosphates (OPs), which are used predominantly as insecticides. OP poisoning can occur in a variety of situations and can be accidental or suicidal. Acute Organophosphate poisoning This is the syndrome recognised by doctors and Poisons Units. Symptoms of Organophosphate Poisoning. Patients exposed to high quantities of these chemicals can develop a variety of symptoms and … Organophosphate intoxication causes cholinergic symptoms early and subsequently a neuropathy with axonal degeneration producing muscle cramping and calf pain along with tingling and burning sensations in the feet. Symptoms occur within 24 hours of exposure and include collapse, breathing problems, sweating, diarrhoea, vomiting, excessive salivation, heart dysrrhythmias, extreme anxiety … Blood/serum, liver, and urine can … Organophosphate Poisoning. The organophosphates (OPs) are derivatives of phosphoric or phosphonic acid. Exposure by inhalation results in the fastest appearance of toxic symptoms, followed by the oral route and finally the dermal route. Symptoms of acute organophosphate poisoning develop during or after exposure, within minutes to hours, depending on method of exposure. OPs have replaced the banned organochlorine compounds and are a major cause of animal poisoning. All signs and symptoms are cholinergic in nature and affect Poisoning can occur due to occupational or accidental exposure, deliberate ingestion, or chemical warfare with nerve gases. 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